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Bariatric surgery and allogeneic hematopoietic stem cell transplantation: a case series

Bone Marrow Transplantation volume 58, pages 1146–1148 (2023)Cite this article

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There is a paucity of literature reporting the impact of bariatric surgery on outcomes following allogeneic hematopoietic stem cell transplantation (HCT). The only study observing this relationship is a case series by Gergis et al., which identified eight patients from 2010 to 2018 with a history of gastric bypass surgery who underwent allogeneic HCT [1]. We investigated morbidity and mortality associated with HCT at our centre among patients with prior bariatric surgery.

Out of 309 patients who underwent allogeneic HCT at our centre between February 2015 and February 2022, seven patients with a history of prior bariatric surgery were identified by examination of medical records. Stage and grade of acute graft-versus-host disease (GvHD) was determined prospectively per the Mount Sinai Acute GvHD International Consortium criteria [2]. Other information, including weight loss during transplant admission, administration of parenteral nutrition, and notable clinical complications was collected retrospectively from the medical record. Due to the small number of patients in the bariatric surgery group, no statistical comparisons were made.

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Data availability

The datasets analysed during the current study are not publicly available to protect patient confidentiality but may be available from the corresponding author on reasonable request.

References

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Authors and Affiliations

  1. Department of Haematology, Fiona Stanley Hospital, Perth, WA, Australia

    Emily Yimei Pereira, Paul Kenneth Cannell, Julian Cooney, Matthew Wright & Duncan Purtill

  2. PathWest Laboratory Medicine, Perth, WA, Australia

    Paul Kenneth Cannell, Julian Cooney, Matthew Wright & Duncan Purtill

  3. Dietetics Department, Fiona Stanley Hospital, Perth, WA, Australia

    Belinda Herrmann

Authors
  1. Emily Yimei Pereira
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  2. Paul Kenneth Cannell
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  3. Julian Cooney
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  4. Matthew Wright
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  5. Belinda Herrmann
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  6. Duncan Purtill
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Contributions

DP conceptualised the research, contributed to the manuscript and provided primary supervision of the research. EYP performed data collection and wrote the manuscript. PKC, JC, MW and BH contributed to the manuscript. All authors approved the final version of the manuscript prior to submission.

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Correspondence to Emily Yimei Pereira.

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The authors declare no competing interests.

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Pereira, E.Y., Cannell, P.K., Cooney, J. et al. Bariatric surgery and allogeneic hematopoietic stem cell transplantation: a case series. Bone Marrow Transplant 58, 1146–1148 (2023). https://doi.org/10.1038/s41409-023-02026-z

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