Table 5 Multivariate analysis: impact of variables on overall survival.

From: Outcomes of primary graft failure in acute myeloid leukemia patients following unrelated transplantation with post-transplant cyclophosphamide: a study from the ALWP/EBMT

Variable

Modalities

HR (95%CI)

P value

ANC recoverya

No

1

 

Yes

0.46 (0.26–0.84)

0.01

KPS

< 90

1

 

≥ 90

0.37 (0.21–0.65)

< 0.001

Age at HSCT

 

1.01 (0.92–1.12)

0.78

Disease status at HSCT

CR

1

 

Not in CR

2.66 (1.50–4.71)

< 0.001

Myeloablative conditioning

No

1

 

Yes

0.75 (0.42–1.33)

0.33

  1. HSCT hematopoietic stem cell transplantation, HR hazard ratio, CI confidence interval, ANC absolute neutrophil count, KPS Karnofsky performance status, CR complete remission.
  2. aANC recovery evaluated as time-dependent covariate.