Fig. 5
From: Cellular senescence and other age-related mechanisms in skeletal diseases
Modes of action for anti-cellular senescence. a Selective elimination of senescent cells by inhibiting the increase in BCL-2 and promoting senescent cell apoptosis. b CAR-T cells were cultured in vitro to target senescent cell-specific antigens to effectively eliminate senescent cells in vivo. c Genetic intervention rejuvenates senescent cells. d Vaccine treatment to prevent aging increased cellular senescence
