Fig. 7

μCT and histomorphometric analysis showed that BMAT depletion in obese mice had improved trabecular bone due to a decrease in mature osteoclasts. a Representative μCT images of the proximal tibia (scale bar = 100 μm). b Tibial trabecular bone volume per total volume (Tb. BV/TV, %; n = 10-11). c Trabecular spacing (Tb.Sp, mm). d Trabecular number (Tb.N, 1/mm). e Trabecular thickness (Tb.Th, mm). f Trabecular structural model index (SMI). g Tibial cortical thickness (Ct.Th, mm). h Tibial cortical area per total area (Ct.Ar/Tt.Ar, %). i Number of osteoclasts per bone perimeter (N.Oc/BPm, number per mm; n = 8). j Eroded surface per bone surface (ES/BS; %). k Number of osteoblasts per bone perimeter (N.Ob/BPm, mm). l Mineralizing surface per bone surface (MS/BS, %). m Mineralizing apposition rate (MAR, μm/d). n Bone formation rate per bone surface (BFR/BS, %). Analyses for b–h were performed as a 2-way ANOVA with uncorrected Fisher’s LSD. Analyses for i–m were performed as a 2-way ANOVA with uncorrected Fisher’s LSD