Fig. 2: Differential GO term enrichment by GSEA following neoadjuvant FFX ± high-dose SBRT. | British Journal of Cancer

Fig. 2: Differential GO term enrichment by GSEA following neoadjuvant FFX ± high-dose SBRT.

From: Favorable histo-molecular remodeling of pancreatic ductal adenocarcinoma after neoadjuvant FOLFIRINOX followed by high-dose stereotactic body radiotherapy

Fig. 2

Selected Gene Set Enrichement Analysis (GSEA) of Gene Ontology (GO) terms based on differential gene expression comparisons between the three main groups (No_NAT, FFX and FXX + SBRT). GO terms are grouped according to biological function (e.g. cell cycle, metabolism). Enrichment scores reflect the relative up- or downregulation of gene sets in each comparison, highlighting functional pathways associated with treatment-specific transcriptional changes. FFX FOLFIRINOX, No_NAT no neoadjuvant treatment group, SBRT stereotactic body radiotherapy, ECM extracellular matrix.

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