Fig. 3: Dot plots showing the proportion of (pre)cancer lesions with aberrant mucin expression.

a Mucin distribution in normal colon. b Mucin distribution in precancerous lesions and their subtypes (serrated polyps: hyperplastic polyps (HP), sessile serrated lesions (SSL), traditional serrated adenomas (TSA); adenomatous polyps: tubular adenomas (TA), villous adenomas (VA), tubulovillous adenomas (TVA)). c Mucin distribution in small intestinal (SIA) and colorectal (CRC) adenocarcinoma and their subtypes. d Mucin distribution in intestinal rare tumour types. For each study, the number of a (pre)cancerous lesion type showing expression of a specific mucin were pooled across all studies examining the same mucin in the same lesion type, resulting in an overall proportion (%) of lesions with aberrant expression of a certain mucin. Expression levels were also compared to those in normal intestinal tissue (if available): green indicates higher expression and red indicates lower expression relative to normal colon. If no comparison with healthy tissue was available, dots are highlighted in grey. If no data were available for a specific mucin in a given lesion subtype, no dot is shown.