Fig. 1: Induction anti-PD-1 therapy combined with radiotherapy maximized anti-tumor response.
From: PD-1 inhibitor improves radiosensitivity by tumor vessel normalization
a Treatment schema. b, c Tumor tissues of Lewis lung cancer (LLC) mouse model and 4T1 breast cancer mouse model were removed at day 18, respectively. d, e Tumor growth curves of different groups from (b, c). Data shown are one representative experiment of two independent experiments (n = 6 mice per group). Statistical significance was calculated by two-way ANOVA. f, h The tumor volume before radiotherapy (day 8) of different group in (b, c), respectively. g, i The tumor weight of tissues in (b, c) respectively. j, k The overall survival curve. Data are presented as means ± SD. P values were calculated using two-tailed unpaired Student’s t-test (f–i).
