Fig. 7: EMSLR involves in EC cell progression via c-MYC-GLUT1 pathway.
From: The involvement of lncRNA EMSLR in the disulfidptosis and progression of endometrial carcinoma
A GSEA used a HALLMARK gene set of EMSLR in TCGA database. B Correlation analysis between EMSLR with MYC using GEPIA. C Western blotting of c-MYC in EMSLR knockdown or overexpression HEC-1-A and ISHIKAWA cell lines. D CCK-8 assay of siNC/siEMSLR with VECTOR/ c-MYC HEC-1-A and ISHIKAWA cells with its analysis. E, F Cell colony formation assay using siNC/siEMSLR with VECTOR/ c-MYC HEC-1-A and ISHIKAWA cells and Statistical analysis. G F-actin staining of siNC/siEMSLR with VECTOR/ c-MYC HEC-1-A and ISHIKAWA cells maintained in glucose free medium for 4 h. Scale bar =50 µm. H, I Cell death staining of siNC/siEMSLR with VECTOR/c-MYC HEC-1-A and ISHIKAWA cells in glucose complete/free/glucose free with 2.85 mM 2ME medium for 12 h and its statistical analysis. N.S: not significant, *P < 0.05, **P < 0.01 and ***P < 0.001.
