Fig. 1: WTAP is upregulated in PCa tissues. | Cancer Gene Therapy

Fig. 1: WTAP is upregulated in PCa tissues.

From: WTAP stabilized by USP7 contributes to enzalutamide resistance in prostate cancer via mediating AKT m6A-modification

Fig. 1: WTAP is upregulated in PCa tissues.The alternative text for this image may have been generated using AI.

A Representative images of WTAP staining by Immuno-histochemistry (IHC) in PCa tissues or prostate normal tissues from a tissue microarray, which contained 60 pairs of patients’ tissues. B, C WTAP staining score was increased in tumors compared to adjacent normal tissues, but had no significant change in different grades. ns, not significant. D WTAP is over-expressed in PCa tumors (n = 493) compared with prostate normal tissues (n = 52) in the TCGA dataset. *P < 0.05. E WTAP protein expression between normal and cancerous specimens was detected by Western blotting assay. The relative WTAP quantification of the Western blotting was measured by using ImageJ software. WTAP expression was increased in Patient 1, Patient 3, and Patient 4.

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