Fig. 4
Analysis of inflammatory mediators in SN following MPTP intoxication displaying differential changes in astrocytic GR mutants compared to controls a Expression levels of selected inflammatory genes measured by RT-qPCR in SN of GRCx30CreERT2 mutant mice compared to control mice 18 and 42 h after saline or MPTP injection. HPRT was used as internal control *p < 0.05 controls vs mutants; #p < 0.05 saline vs MPTP injected; error bars are SEM. n = 5 mice/group. b Protein level of TNF-α in SN of control and GRCx30CreERT2 mutant mice 3 days after saline or acute MPTP injections. ##p < 0.02 saline vs MPTP injected, *p < 0.05 controls vs mutants MPTP. Error bars represent SEM. n = 4 mice/group
