Fig. 7
From: The lncRNA HOTAIR transcription is controlled by HNF4α-induced chromatin topology modulation
HNF4α binding to HOTAIR regulative sequences associates to chromatin topological changes a 3C assays of the HDE-HOTAIR locus in SW480 and SW620 cells. Values derived from three independent experiments are reported as means ± S.E.M. and expressed with respect to the control sample. Statistically significant differences are reported (**p < 0.01). b 3C assay of the HDE-HOTAIR locus in HNF4α- or mock-infected SW480 cells. Values derived from three independent experiments are reported as means ± S.E.M. and expressed with respect to the control sample. Statistically significant differences are reported (*p < 0.05). c 3C assay of the HDE-HOTAIR locus in SW620 cells treated or not with TGFβ. Values derived from three independent experiments are reported as means ± S.E.M. and expressed with respect to the control sample. Statistically significant differences are reported (*p < 0.05). d 3 C assay of the HDE-HOTAIR locus in HNF4α-silenced (for 48 h) (siHNF4α) SW620 cells, compared with control siGFP cells (siCtr). Values derived from three independent experiments are reported as means ± S.E.M. and expressed with respect to the control sample. Statistically significant differences are reported (*p < 0.05)
