Fig. 2 | Cell Death & Differentiation

Fig. 2

From: TC2N, a novel oncogene, accelerates tumor progression by suppressing p53 signaling pathway in lung cancer

Fig. 2The alternative text for this image may have been generated using AI.

Effects of ectopic expression of TC2N on lung cancer cell proliferation and apoptosis in vitro. a Knockdown of TC2N in H460 cells and overexpression of TC2N in HBE cells were identified by WB assay. ACTIN serves as a loading control. b MTS assays were carried out in H460 cells expressing the negative control or shRNA of TC2N and in HBE cells expressing the vector control or TC2N. *P < 0.05; **P < 0.01. c, d Flow cytometry assays were used to examine the effect of TC2N on cell cycle (c) and cell apoptosis (d). Error bars indicate SD (n = 3)

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