Fig. 5 | Cell Death & Differentiation

Fig. 5

From: Reprogramming miRNAs global expression orchestrates development of drug resistance in BRAF mutated melanoma

Fig. 5

Conditioned media from drug-resistant melanoma cells is enriched in several proinflammatory and pro-angiogenic factors. a The levels of 27 cytokines determined in the supernatants from M14S and WM266SS cells and from their resistant counterparts. b, c WM266R and M14R cells conditioned media overproducing several cytokines and chemokines (fold change significance greater than 1.3) divided in three distinct groups with a high, medium and low degree of upregulation. d Cell index (left panel) and Slope induction (right panel) results obtained through xCELLigence Real Time Cell Analysis showing that conditioned media from WM266R melanoma cells inducing cell migration as compared to cell media from sensitive counterparts and CTRL media

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