Fig. 5

PCD in the mouse heart during early embryonic development. a–d Sagittal sections of a transgenic embryo at E9.5 and of an E11.5 heart. b, d Magnification of the boxed areas: bright YFP⁺ signals (white arrows) mark PCD cells or PCD bodies. cCasp3 cleaved caspase 3, Hoechst nuclear signal, V ventricle, OFT outflow tract, RA right atrium, LA left atrium, Tr trabeculae, and iVS intraventricular septum. Bars are 200 µm (a), 10 µm (b), 100 µm (c), and 10 µm (d)