Fig. 9: Gas6/MerTK signaling promotes NSCLC cell proliferation. | Cell Death & Differentiation

Fig. 9: Gas6/MerTK signaling promotes NSCLC cell proliferation.

From: KPNB1-mediated nuclear translocation of PD-L1 promotes non-small cell lung cancer cell proliferation via the Gas6/MerTK signaling pathway

Fig. 9

a EdU assay was performed in H1299 and HCC827 cells transfected with si-MerTK or si-NC with or without Gas6 stimulation for 24 h (Scale bar: 2 mm). b Western blot assay of p-MerTK, MerTK, p-AKT, AKT, p-Erk and Erk. c The proposed mechanistic model underlying the nPD-L1-mediated Gas6/MerTK signaling stimulating NSCLC cell proliferation. Data were presented as the mean ± SD. Data were analysed using one-way ANOVA analysis followed by Bonferroni’s post hoc test. **P < 0.01; ***P < 0.001 vs. control or as indicated.

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