Fig. 1: SPAG5 is overexpressed in breast cancer tissues and anticorrelated with miR-10b-3p. | Cell Death & Differentiation

Fig. 1: SPAG5 is overexpressed in breast cancer tissues and anticorrelated with miR-10b-3p.

From: Aberrant transcriptional and post-transcriptional regulation of SPAG5, a YAP-TAZ-TEAD downstream effector, fuels breast cancer cell proliferation

Fig. 1

A, B Heatmaps SPAG5 and miR-10b-3p expression in METABRIC cohort (A) and in TCGA dataset (B). C, D Boxplot SPAG5 expression in tumoral versus normal breast tissues in METABRIC cohort (C) and in TCGA dataset (D). E, F Boxplot SPAG5 expression in Lum-A, Lum-B, Her2, and basal-like breast cancer histotypes in METABRIC cohort (E) and in the TCGA dataset (F). G, H Kaplan–Meier plots show survival analysis of breast cancer patients with low and high expression of SPAG5 in METABRIC cohort (G) and in the TCGA dataset (H).

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