Table 2 Prognosis of highly correlated breast cancer patients with high levels of YAP signature and high levels of SPAG5.

From: Aberrant transcriptional and post-transcriptional regulation of SPAG5, a YAP-TAZ-TEAD downstream effector, fuels breast cancer cell proliferation

N patients = 996

Cox multivariate

HR [95% CI]

P value

YAPsignhigh + SPAG5high

and

YAPsignlow + SPAG5low

1.88 [1.39–2.53]

3.8e–05

  1. Cox-multivariate analysis of breast cancer Metabric patients with high and low levels of YAP signature and SPAG5 adjusted for T, N, stage, hystotype, age, and menopausal state (N = 996 patients).