Fig. 3: EAC organoids display mitotic defects similar to EAC cultured cells. | Cell Death & Differentiation

Fig. 3: EAC organoids display mitotic defects similar to EAC cultured cells.

From: Evidence that polyploidy in esophageal adenocarcinoma originates from mitotic slippage caused by defective chromosome attachments

Fig. 3

a The indicated control and EAC organoids were fixed and stained to detect tubulin (red in the merged images), the centromeric marker CREST (green in the merged images), and DNA (blue in the merged images). Bars, 10 µm. b Graph showing the quantification of mitotic defects observed in the indicated organoids; 20 organoids in 2 independent experiments were analyzed for each group. c Graph showing the frequency of phenotypes observed in the organoids described in (a, b).

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