Fig. 4: Genes involved in chromosome attachments are altered in EAC cells, organoids, and tumors. | Cell Death & Differentiation

Fig. 4: Genes involved in chromosome attachments are altered in EAC cells, organoids, and tumors.

From: Evidence that polyploidy in esophageal adenocarcinoma originates from mitotic slippage caused by defective chromosome attachments

Fig. 4

Diagrams showing the frequency and nature of SNVs, indels, and copy number alterations of genes involved in chromosome attachment in cell lines and organoids (a), and EAC cases (n = 379) from the Oesophageal Cancer Clinical And Molecular Stratification (OCCAMS) consortium (b). Total proportion of cases altered by individual gene are listed at the bottom (a) or at the left (b) of the oncoplot.

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