Fig. 7: FLO cells with scattered chromosomes display an increase in lateral kinetochore-microtubule attachments. | Cell Death & Differentiation

Fig. 7: FLO cells with scattered chromosomes display an increase in lateral kinetochore-microtubule attachments.

From: Evidence that polyploidy in esophageal adenocarcinoma originates from mitotic slippage caused by defective chromosome attachments

Fig. 7

a CPA and FLO cells were fixed and stained to detect the indicated epitopes. The insets show a 5× magnification of selected kinetochores. Bars, 10 µm. b Graph showing the quantification of lateral kinetochore-microtubule attachments in CPA and FLO cells. 100 kinetochores were counted in each group; n = 11 independent CPA cells, n = 10 independent FLO cells and n = 9 independent FLO cells with scattered chromosomes (S). Bars indicate standard errors; *p < 0.05 (Mann–Whitney U test).

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