Fig. 7: GLI1, MVP and P-p70S6K1 expression are positively correlated in human CS tissues. | Cell Death & Differentiation

Fig. 7: GLI1, MVP and P-p70S6K1 expression are positively correlated in human CS tissues.

From: Constitutive GLI1 expression in chondrosarcoma is regulated by major vault protein via mTOR/S6K1 signaling cascade

Fig. 7

A Western blot results showing expression of GLI1, MVP, P-p70S6K1, and P-AKT in tissues from normal articular cartilage, osteochondroma, and conventional CS. Densitometry was performed to quantify the relative expression of these proteins as shown in the right box plot. B Western blot results showing expression of GLI1, MVP, P-p70S6K1, and P-AKT in four CS cell lines. C Representative images of positive or negative IHC staining results of GLI1, MVP, and P-p70S6K1. D Statistical analysis of IHC staining results from 71 human conventional CS tissues. E Statistical analysis of positive IHC staining results for MVP, GLI1, and P-p70S6K1 in five normal cartilage and 71 conventional CS tissues. F Statistical analysis showing correlation between GLI1 and MVP in IHC staining results of 71 human conventional CS tissues. G Statistical analysis for the correlation between P-p70S6K1 and GLI1 based on IHC staining results of 71 human conventional CS tissues. H Statistical analysis for the correlation between P-p70S6K1 and MVP based on IHC staining results of 71 human conventional CS tissues.

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