Fig. 4: Kupffer cells are the primary cell type phagocytizing desialylated platelets in the liver. | Cell Death & Differentiation

Fig. 4: Kupffer cells are the primary cell type phagocytizing desialylated platelets in the liver.

From: Kupffer cell receptor CLEC4F is important for the destruction of desialylated platelets in mice

Fig. 4

A, B Representative confocal microscopic images. CD41 marks platelets, F4/80 marks Kupffer cells, CD31 labels sinusoidal endothelium, and hepatocytes were detected by autofluorescence. C Pseudocolored TEM micrographs of WT or Clec4f−/− ultrathin sections. Red arrow marks a phagocytized platelet. Blue arrows mark potential interactions between platelets and sinusoidal endothelium.

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