Fig. 2: Ddr2Adipo mice have increased bone mass.
From: Targeting adipocytic discoidin domain receptor 2 impedes fat gain while increasing bone mass
A μCT images of femurs of 3-month-old Ddr2Adipo and WT littermates. B Quantitative μCT analysis of trabecular bone. BMD bone mineral density, BV/TV bone volume per tissue volume, Tb.No, trabecular number, Tb.Sp. trabecular separation, Tb.Th. trabecular thickness. C Quantitative μCT analysis of cortical bone. Ct. Th. cortical thickness, Ct. Ar. cortical area. D μCT analysis of diaphyseal bone area. E Bending tests analysis of Ddr2Adipo and WT femoral stiffness. F Yield Force of Ddr2Adipo and WT femoral bone. G Ultimate force. Data are presented as mean ± SEM. n = 6 femurs from 6 mice for WT mice, n = 7 femurs from 7 mice for Ddr2Adipo mice. *P < 0.05; **P < 0.01; ***P < 0.001 as determined by unpaired t-test.
