Fig. 2: Downregulation of SP100-AS1 exacerbated radio-induced cell death. | Cell Death & Differentiation

Fig. 2: Downregulation of SP100-AS1 exacerbated radio-induced cell death.

From: A novel long noncoding RNA SP100-AS1 induces radioresistance of colorectal cancer via sponging miR-622 and stabilizing ATG3

Fig. 2

A The cellular survival curves of HCT116 following SP100-AS1 knockdown using siRNA. B The cell viability of HCT116 cells at a radiation dose of 4 Gy. C The cellular survival curves of SW480 following SP100-AS1 knockdown. D The cell viability of SW480 following 4 Gy of IR. E The expression of γ-H2AX in HCT116 and SW480 cell lines following SP100-AS1 knockdown and the gray intensity histogram of γ-H2AX expression. F Cell apoptosis was evaluated by flow cytometry, and the apoptotic cell percentage was statistically analyzed. n = 3, *P < 0.05, **P < 0.01 compared with the indicated group.

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