Fig. 5: DNMT1 regulate ER stress related-gene in late stage of terminal erythroblasts.

A Rank-based gene set enrichment pathways by DNMT1 significantly regulated. The images of GSEA demonstrated the key pathways which all involved in ER stress. B The FPKM value of N-linked glycosylation in ER. C The FPKM value of Disulfide bound formation in ER. D The FPKM value of Molecular chaperones in ER. E The FPKM value of protein export by translocation in ER. F The FPKM value of pathway of UPR sensor and downstream molecular in ER. * p < 0.05, ** p < 0.01.