Table 1 Clinical and pathological characteristics of 55 diagnosed ECC patients.

From: The AKR1C1–CYP1B1–cAMP signaling axis controls tumorigenicity and ferroptosis susceptibility of extrahepatic cholangiocarcinoma

Clinical features

No. of cases

AKR1C1 positive cases (%)

P value

Gender

  

0.262

 Male

35

23 (65.7)

 

 Female

20

16 (80.0)

 

Age (years)

  

0.090

 ≤60

27

22 (81.5)

 

 >60

28

17 (60.7)

 

TNM stage

  

0.0038**

 I/II

8

3 (37.5)

 

 III/IV

47

36 (76.6)

 

Tumor size

  

0.003**

 <3 cm

18

8 (44.4)

 

 ≥3 cm

37

31 (83.8)

 

Histologic grade

  

0.007**

 Well

20

9 (45.0)

 

 Moderate

21

17 (81.0)

 

 Poor

14

13 (92.9)

 

Lymph node metastasis

  

0.030*

 No

19

10 (52.6)

 

 Yes

36

29 (80.6)

 
  1. *P values < 0.05 were considered statistically significant.
  2. **P < 0.01.