Fig. 1: The dysregulation of fatty acid metabolism in septic patients. | Cell Death & Differentiation

Fig. 1: The dysregulation of fatty acid metabolism in septic patients.

From: Fatty acid synthesis promotes mtDNA release via ETS1-mediated oligomerization of VDAC1 facilitating endothelial dysfunction in sepsis-induced lung injury

Fig. 1

A Partial least squares discriminant analysis (PLS-DA) showing the separation of septic patients from healthy controls. B Pie charts of Superclass differential metabolites. C, D Heatmap and KEGG enrichment of metabolic analysis data in septic patients. E–G The levels of FASN, sVCAM-1, and sE-selectin were measured by ELISA in healthy controls (n = 10) and septic patients (n = 18). H, I The correlation analysis of FASN with sVCAM-1 and sE-selectin. All data were expressed as the mean ± SD. Student’s t test was used for (E–G). Simple linear regression and Spearman correlation coefficients were used for (H, I).

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