Fig. 7: Supervised clustering for targeted intervention. | Cell Death & Differentiation

Fig. 7: Supervised clustering for targeted intervention.

From: Potential of biomarker-based enrichment strategies to identify critically ill patients for emerging cell death interventions

Fig. 7

A Number of patients per category. B 30-days mortality per category. C Dynamic of IL-18, IL-1Ra, and MDA in IL-1Ra + /IL-18- patients. D Dynamic of IL-18, IL-1Ra, and MDA in IL-1Ra + /IL-18+ patients. Patients are considered IL-1Ra-positive if IL-1Ra was detected during the first 7 ICU days; IL-18-positive if IL-18 peaked above 100 pg/mL detected during the first 7 ICU days; and MDA-positive if MDA peaked above 14.25 µM during the first 7 ICU days.

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