Table 1 Execution and timing control defects in PCD lead to the bulged tail phenotype in the grp-1 background.
Genotype | % animals with a bulged tail |
|---|---|
Wild-type | 0% |
grp-1(gm350) | 6% |
Defects in execution of cell death result in an aberrant bulged tail | |
egl-1(n1084n3082) | 2% |
grp-1(gm350); egl-1(n1084n3082) | 87% |
ced-9(n1950) | 5% |
grp-1(gm350) ced-9(n1950) | 94% |
ced-4(n1162) | 8% |
ced-4(n1162) grp-1(gm350) | 94% |
ced-3(n717) | 1% |
grp-1(gm350); ced-3(n717) | 86% |
ced-3(n2427) | 0% |
grp-1(gm350); ced-3(n2427) | 92% |
ced-3(n2923) | 1% |
grp-1(gm350); ced-3(n2923) | 43% |
Defects in timing control of cell death result in an aberrant bulged tail | |
ced-8(n1891) | 0% |
grp-1(gm350); ced-8(n1891) | 80% |
Defects in engulfment do not cause an aberrant bulged tail | |
ced-1(e1735) | 0% |
ced-1(e1735); grp-1(gm350) | 8% |
ced-12(bz187) | 1% |
ced-12(bz187); grp-1(gm350) | 8% |
Defects in DNA degradation do not cause an aberrant bulged tail | |
cps-6(ok1718) | 0% |
cps-6(ok1718); grp-1(gm350) | 8% |
cnt-1(tm2313) | 1% |
cnt-1(tm2313); grp-1(gm350) | 12% |
