Fig. 3: Single-cell expression profiling of human mesothelioma.
From: Fibroblast-like cells in mesothelioma can derive from tumor cells
A UMAP visualization of n = 8 005 cells (median nGene = 1153, nUMI = 3 472) clustering into 14 different populations. B Sample origins. C Normal or Tumor identification of cells based on scRNA-Seq CNV calls by Numbat. D Cell fractions in each of the 5 different samples. E Dot plot of the top 10 significant Hallmark Pathways enriched in specific clusters. The number of Differentially Expressed Genes in clusters (FDR < 0.05, log2FC > 1) is indicated under the name of the clusters.
