Retraction Note to: Cell Death and Disease https://doi.org/10.1038/s41419-019-1374-y, published online 04 February 2019
The Editors-in-Chief have retracted this article. After publication, concerns were raised regarding highly similar images within the article and with another publication from the same Authors. Specifically:
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Fig. 2A, 9ug/kg and Fig. 6A, Rh-chemerin appear to overlap (resized)
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Fig. 3A, ChemR23-siRNa and Fig. 5A, r-Robo1 [1] appear to be highly similar
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Fig. 3A, Vehicle and Fig. 3A, ChemR23 siRNA appear to partially overlap
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Fig. 3A, Sham and Fig. 3A, scramble siRNA appear to partially overlap
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Fig. 5A, Rh-Chemerin (second and third brain slice from the top) and Fig. 4A, r-Slit2 (second and third brain slice from the top) [1] appear to be highly similar
The Authors confirmed only some similarities but were unable to provide a sufficient response to the other concerns raised. Therefore, the Editors-in-Chief no longer have confidence in the presented data.
None of the authors responded to correspondence from the Publisher about this retraction notice.
Reference
Kaur H, Xu N, Doycheva DM, Malaguit J, Tang J, Zhang JH. Recombinant Slit2 attenuates neuronal apoptosis via the Robo1-srGAP1 pathway in a rat model of neonatal HIE. Neuropharmacology. 2019;158:107727. https://doi.org/10.1016/j.neuropharm.2019.107727.
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Zhang, Y., Xu, N., Ding, Y. et al. Retraction Note: Chemerin reverses neurological impairments and ameliorates neuronal apoptosis through ChemR23/CAMKK2/AMPK pathway in neonatal hypoxic–ischemic encephalopathy. Cell Death Dis 16, 768 (2025). https://doi.org/10.1038/s41419-025-08183-x
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DOI: https://doi.org/10.1038/s41419-025-08183-x