Table 1 Baseline characteristics.

From: Androgen receptor-dependent DRAM1 activation drives autophagic resistance to BRAF inhibitors in BRAFV600-mutant melanoma

Characteristic

Patients (N = 30)

Age (years)

 

 Median (range)

55 (45–78)

Gender, n (%)

 

 Male

14 (46.67%)

 Female

16 (55.33%)

PS(ECOG)

 

 0

27 (90%)

 1

3 (10%)

Stage, n (%)

 

 III

30 (100%)

BRAF mutation status at diagnosis, n (%)

 

 V600E

19 (63.33%)

 V600K

8 (26.67%)

 V600R

3 (10%)

Type of lymph-node involvement, n (%)

 

 Microscopic

11 (36.67%)

 Macroscopic

12 (40%)

 Unknown

7 (23.33%)

Primary tumor ulceration, n (%)

 

 Yes

19 (63.33%)

 No

11 (36.67%)

  1. PS (ECOG): Performance Status as defined by the Eastern Cooperative Oncology Group scale. This is a standardized scale (ranging from 0 to 5) used to assess a patient’s level of daily functioning and physical ability, where 0 denotes perfect health, and 5 indicates death. The specific criteria are: 0-Asymptomatic; 1-Symptomatic but fully ambulatory; 2-In bed <50% of the day; 3-In bed >50% of the day; 4 -Bedbound; 5-Dead.
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