Fig. 1: mRNA analysis of MP-HJ-1b in HeLa cells.
From: A novel microtubule inhibitor promotes tumor ferroptosis by attenuating SLC7A11/GPX4 signaling
A Volcano plot of the transcriptomic data (MP-HJ-1b vs Ctrl). Genes with P < 0.05 were considered differentially expressed genes (DEGs). B Significant GO terms and KEGG pathways related to genes upregulated by MP-HJ-1b stimulation. C Significant GO terms and KEGG pathways related to genes downregulated by MP-HJ-1b stimulation. D Gene interaction network of the top 50 hub differentially expressed genes (MP-HJ-1b vs Ctrl). The size of each gene node was determined by its frequency in the network, i.e., a larger node size means a higher frequency.
