Table 1 Clinical biochemical data of patients (CCa and CIN) and healthy controls.
From: A novel microtubule inhibitor promotes tumor ferroptosis by attenuating SLC7A11/GPX4 signaling
Item | Control | CIN | P value | Control | CCa | P value | CIN | CCa | P value |
|---|---|---|---|---|---|---|---|---|---|
(n = 230) | (n = 205) | (n = 230) | (n = 311) | (n = 205) | (n = 311) | ||||
SCC (ng/ml) | 0.18 (0.12) | 0.86 (0.64) | <0.001a | 0.18 (0.12) | 1.53 (3.64) | <0.001a | 0.86 (0.64) | 1.53 (3.64) | <0.001a |
CA-125 (U/ml) | 11.45 (6.21) | 12 (8.1) | 1.000a | 11.45 (6.21) | 13.2 (8.88) | <0.001a | 12 (8.1) | 13.2 (8.88) | 0.002a |
ALT (U/L) | 13.95 (10.4) | 12.3 (7.35) | 0.055a | 13.95 (10.4) | 12.3 (9.2) | 0.049a | 12.3 (7.35) | 12.3 (9.2) | 1.000a |
AST (U/L) | 18.1 (6.025) | 16.9 (5.9) | 0.019a | 18.1 (6.025) | 16.7 (6.3) | 0.002a | 16.9 (5.9) | 16.7 (6.3) | 1.000a |
GGT (U/L) | 15 (8.25) | 14 (7) | 0.033a | 15 (8.25) | 15 (9) | 1.000a | 14 (7) | 15 (9) | 0.018a |
Cho (mM) | 5.04 ± 0.93 | 4.67 ± 0.89 | <0.001 | 5.04 ± 0.93 | 4.65 ± 0.87 | <0.001 | 4.67 ± 0.89 | 4.65 ± 0.87 | 0.767 |
HDL-C (mM) | 1.46 (0.47) | 1.34 (0.375) | 0.001a | 1.46 (0.47) | 1.3 (0.35) | <0.001a | 1.34 (0.375) | 1.3 (0.35) | 0.076a |
LDL-C (mM) | 2.83 (1.0325) | 2.61 (1.055) | 0.044a | 2.83 (1.0325 | 2.66 (0.94) | 0.082a | 2.61 (1.055) | 2.66 (0.94) | 1.000a |
TG (mM) | 1.03 (0.84) | 0.96 (0.615) | >0.050a | 1.03 (0.84) | 1.05 (0.68) | >0.050a | 0.96 (0.615) | 1.05 (0.68) | >0.050a |
