Fig. 5: Beneficial role of HO-1 in promoting diabetic wound healing.
From: Effective protective mechanisms of HO-1 in diabetic complications: a narrative review
Diabetic wounds have excessive oxidative stress and inflammation. Up-regulation of HO-1 will reduce oxidative stress and pro-inflammatory factors, and also promote cell viability, migration, proliferation, and angiogenesis, thus promoting diabetic wound healing.
