Fig. 5: Mechanistic regulation of pyroptosis by circRNAs in cardiovascular diseases (By Biorender). | Cell Death Discovery

Fig. 5: Mechanistic regulation of pyroptosis by circRNAs in cardiovascular diseases (By Biorender).

From: Circular RNAs modulate cell death in cardiovascular diseases

Fig. 5

Cell pyroptosis is dependent on caspase-1 and is characterized by the release of large amounts of pro-inflammatory factors, with or without sponging miRNA. The figure highlights pro-pyroptotic circRNAs in the context of CVD progression like circ-0006332, circ-Helz and circ-USP9x, underscoring their therapeutic potential.

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