Fig. 3: Expression of Plin4 in B[a]P-induced hippocampal neuronal death.
From: Plin4 modulates lipid droplet accumulation and ferroptosis in neurons exposed to benzo[a]pyrene
![Fig. 3: Expression of Plin4 in B[a]P-induced hippocampal neuronal death.](http://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fs41420-025-02747-8/MediaObjects/41420_2025_2747_Fig3_HTML.png?as=webp)
a Experimental workflow summarizing the steps of the current analysis. b Survival rate changes of primary mouse hippocampal neurons under different concentrations of BPDE treatment. The survival rate decreases as BPDE concentration increases. c Relative expression of Plin4 in primary mouse hippocampal neurons under BPDE treatment, with a significant upregulation of Plin4 expression. d Survival rate changes of HT22 cells under different concentrations of BPDE treatment, showing a dose-dependent decrease in survival rate as BPDE concentration increases. e Relative expression of Plin4 in HT22 cells under BPDE treatment, with a significant upregulation of Plin4 expression as BPDE concentration increases. Data are presented as mean ± SEM(n = 6 per group, BPDE concentrations in μM) *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001.
