Fig. 6: Signaling pathway analysis comparing SARS-CoV-2-infected Calu-3 cells untreated and pre-treated with Tetrandrine at 5 μM.

A Volcano plot comparing untreated SARS-CoV-2-infected Calu-3 cells (left) and pre-treated cells with Tetrandrine at 5 µM (right). Cellular differentially abundant proteins (DAPs) are shown in blue, and viral proteins are shown in red; B Protein network analysis using STRING; C Pathway enrichment analysis performed using the STRING app in Cytoscape, with the WikiPathway, Reactome, and KEGG databases.