Table 3 Univariate and multivariate survival analyses (Cox regression model) of various factors in 106 patients with ovarian cancer.
From: SREBP1 knockdown triggers ferroptosis by suppressing the Nrf2-XCT/GPX4 axis in ovarian cancer
Characteristics | B | SE | Wald | HR (95% CI) | p-value |
|---|---|---|---|---|---|
Univariate survival analyses | |||||
SREBP1 | 2.494 | 0.480117 | 26.994 | 12.115 (4.728–31.047) | <0.001*** |
Age (years) | 0.611 | 0.292 | 4.369 | 1.843 (1.039–3.269) | 0.037* |
Type of pathology | −0.808 | 0.341 | 5.595 | 0.446 (0.228–0.871) | 0.018* |
Tumor size (cm) | 3.101 | 2.652 | 1.368 | 22.224 (0.123–4017.059) | 0.242 |
Clinical staging | 0.465 | 0.368 | 1.595 | 1.592 (0.774–3.277) | 0.207 |
Lymph node metastasis | 1.801 | 0.29 | 38.479 | 6.057 (3.428–10.701) | <0.001*** |
Distant metastasis | 1.843 | 0.304 | 36.664 | 6.315 (3.478–11.466) | <0.001*** |
Tumor recurrence | 3.434 | 1.391 | 6.093 | 30.989 (2.028–473.463) | 0.014* |
Ki67 | 3.555921 | 0.755786 | 22.136372 | 35.02 (7.961–154.043) | <0.001*** |
PDL1 | 0.607 | 0.283 | 4.58 | 1.834 (1.052–3.197) | 0.032* |
Multivariate survival analyses | |||||
SREBP1 | 1.329 | 0.548 | 5.873 | 3.777 (1.289–11.067) | 0.015* |
Ki67 | 2.729 | 0.831 | 10.785 | 15.316 (3.005–78.062) | 0.001** |
