Fig. 1: Schematic illustration of the fabrication and utilization of SFRP2 ~ PDA@GelMA nerve conduit.

A GelMA hydrogel nanofilm was fabricated based on electrospinning technology. B GelMA nanofilm was coated with PDA. C PDA@GelMA nanofilm was modified with SFRP2 protein to obtain the SFRP2 ~ PDA@GelMA nanofilm. D The SFRP2 ~ PDA@GelMA nanofilm was curled into a nerve conduit. E The SFRP2 ~ PDA@GelMA conduit was used to enhance the repair of PNI through promoting angiogenesis and activation of Schwann cells.