Fig. 6: In vivo evaluation of sciatic nerve angiogenesis. | NPG Asia Materials

Fig. 6: In vivo evaluation of sciatic nerve angiogenesis.

From: Polydopamine-modified hydrogel nanofibers for sustained SFRP2 release: synergistic promotion of angiogenesis and nerve regeneration

Fig. 6

A Schematic diagram of the surgical methods in different treatment groups. The yellow rectangle represents the surgical segment of the mouse sciatic nerve, the narrow part represents the sciatic nerve subjected to clamp injury, and the translucent rectangles represents the different nerve conduits. B H&E staining of sciatic nerves in different treatment groups. Black indicates the hydrogel nerve conduit. Scale bar: 300 μm. C Representative images of CD31 staining in different groups. Scale bar: 150 μm. D Quantitative analysis of microvessel density (CD31 staining) in different groups. E Representative images of CD34 staining in different groups. Scale bar: 80 μm. F Quantitative analysis of CD34 positive area in different groups. *p < 0.05, **p < 0.01, ***p < 0.001, ns not significant.

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