Fig. 3 | Polymer Journal

Fig. 3

From: Expanding toolkit for RNP granule transcriptomics

Fig. 3

Semiextractable RNA as a hallmark of granular RNA. RNAs within phase-separated structures (arcRNAs) remain in the protein-rich phase when extracted using acid guanidinium thiocyanate-phenol‒chloroform (AGPC) reagents (e.g., TRIzol). However, these RNAs can be recovered in the aqueous phase by needle shearing or heat treatment

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