Fig. 5

DNA droplets computing an AND gate. a Scheme of a DNA droplet AND gate. The mixed droplets are defined as [0] state, whereas the demixed droplets are the [1] state. The state change from a mixed state to a demixed state occurs only upon the input of two specific nucleic acid sequences. b Cleavage process of a six-branched linker. Toehold sequences for the SDR were applied to the receptor mechanism (Receptor 1, Receptor 2). Input DNAs (Input 1, Input 2) start SDR from the receptors, deactivating the cross-bridging capability. c Microscopy images of a DNA droplet AND gate for each input pattern. Scale bar: 10 μm. Reproduced [31] with permission. Copyright 2022, Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim