Table 2 In vitro antibacterial activities (Inhibition rate/%) of the Nitrogen-containing ionic drugs against phytopathogenic bacteria
From: Drug repurposing strategy part 1: from approved drugs to agri-bactericides leads
Compounds | concentration (μg ml−1) | Inhibition rate/% | ||
|---|---|---|---|---|
Xoo | Xac | Pa | ||
1-Butylpyridinium bromide | 100 | 30.77 ± 1.91 | 2.17 ± 0.93 | 0 ± 0 |
N-butyl-4-methylpyridinium chloride | 100 | 14.53 ± 1.11 | 0 ± 0 | 0 ± 0 |
1-Hexadecylpyridinium bromide | 100 | 100 ± 0 | 100 ± 0 | 100 ± 0 |
1-Dodecylpyridinium bromide | 100 | 100 ± 0 | 100 ± 0 | 100 ± 0 |
1-Methyl-3-n-octylimidazolium tetrafluoroborate | 100 | 98.58 ± 0 | 91.33 ± 0.31 | 5.3 ± 2.15 |
1,1’-Di-n-heptyl-4,4’-Bipyridinium dibromide | 100 | 98.91 ± 1.09 | 98.45 ± 0 | 0 ± 0 |
N-N-octadecyl-4-stilbazole bromide | 100 | 0 ± 0 | 9.03 ± 1.66 | 0 ± 0 |
1-Tetradecylpyridinium chloride | 100 | 96.72 ± 1.91 | 100 ± 0 | 0 ± 0 |
1-Hexyl-3-methylimidazolium bromide | 100 | 0 ± 0 | 0 ± 0 | 92.56 ± 0.19 |
1-Butyl-3-methylimidazolium chloride | 100 | 0 ± 0 | 0 ± 0 | 9.22 ± 3.05 |
1-propyl-3-Methyl iMidazoliuM | 100 | 0 ± 0 | 0 ± 0 | 0 ± 0 |
3-Methyl-1-octylimidazolium chloride | 100 | 99.45 ± 0.55 | 40 ± 2.35 | 6.17 ± 7.63 |
1-Hexyl-3-methylimidazolium chloride | 100 | 99.18 ± 0 | 0 ± 0 | 29.24 ± 14.3 |
1-Decyl-3-methylimidazolium chloride | 100 | 98.64 ± 0.55 | 98.53 ± 0 | 72.92 ± 8.39 |
1-Dodecyl-3-methylimidazolium chloride | 100 | 98.36 ± 0.27 | 100 ± 0 | 98.66 ± 0.76 |
1-Hexadecyl-3-methylimidazolium chloride monohydrate | 100 | 100 ± 0 | 100 ± 0 | 98.09 ± 0.19 |
1-Decyl-3-methylimidazolium bromide | 100 | 100 ± 0 | 99.41 ± 0.29 | 0 ± 0 |
BenzyldodecyldiMethy | 100 | 100 ± 0 | 100 ± 0 | 100 ± 0 |
Benzyldimethylhexadecylammonium chloride | 100 | 100 ± 0 | 100 ± 0 | 98.28 ± 0.19 |
Tetradecyldimethylbenzylammonium chloride | 100 | 93.99 ± 0.55 | 100 ± 0 | 100 ± 0 |
Stearyldimethylbenzylammonium chloride | 100 | 100 ± 0 | 100 ± 0 | 91.04 ± 6.87 |
Dodecyldimethylbenzylammonium chloride | 100 | 100 ± 0 | 100 ± 0 | 25.62 ± 1.91 |
Octenidine dihydrochloride | 100 | 100 ± 0 | 100 ± 0 | 100 ± 0 |
Miltefosine | 100 | 99.18 ± 0.27 | 99.46 ± 0.18 | 34.54 ± 2.32 |
Hexadecyl trimethyl ammonium bromide | 100 | 100 ± 0 | 100 ± 0 | 100 ± 0 |
Benzyldimethylhexadecylammonium chloride | 100 | 100 ± 0 | 100 ± 0 | 100 ± 0 |
Domiphen bromide | 100 | 95.81 ± 0.22 | 94.03 ± 1.05 | 96.69 ± 0.5 |
Cetylpyridinium chloride | 100 | 77.76 ± 0.29 | 87.66 ± 0 | 93.25 ± 3.37 |
