Table 1 Clinicopathological characteristics of 215 patients wi1th colorectal cancer after surgery.

From: Developing and validating a Modified Cachexia Index to predict the outcomes for colorectal cancer after radical surgery

Variable

ALL (215)

Low mCXI (60)

High mCXI (155)

P value

Age (years)

58.4 ± 12.8

60.0 ± 14.4

57.8 ± 12.1

0.268

Male sex, n (%)

124 (57.7%)

29 (48.3%)

95 (61.2%)

0.085

BMI (kg/m2)

22.9 ± 3.2

22.1 ± 3.5

23.2 ± 3.1

0.02

SMI (cm2/m2)

43.1 ± 4.3

40.6 ± 4.7

44.1 ± 3.7

<0.01

WBC (×109/L)

5.8 ± 1.9

6.1 ± 2.0

5.7 ± 1.8

0.191

Neutrophil (×109/L)

3.7 ± 1.8

4.6 ± 2.5

3.4 ± 1.3

<0.01

Lymphocyte (×109/L)

1.6 ± 0.6

1.2 ± 0.6

1.7 ± 0.6

<0.01

Platelet (×109/L)

216.9 ± 83.7

213.0 ± 101.0

218.4 ± 77.8

0.674

Hemoglobin (g/L)

122.7 ± 24.6

117.0 ± 24.3

124.9 ± 24.4

0.035

Total cholesterol

4.3 ± 1.1

4.2 ± 1.2

4.4 ± 1.0

0.182

Albumin (g/L)

41.3 ± 4.3

39.8 ± 5.4

41.9 ± 3.7

0.007

Creatinine

65.5 ± 18.0

59.9 ± 18.9

67.7 ± 17.1

0.004

Blood urea nitrogen

5.2 ± 1.5

5.7 ± 2.2

5.0 ± 1.2

0.021

CRP (mg/L)

8.6 ± 19.8

13.1 ± 26.1

6.9 ± 16.5

0.085

CEA (ng/ml)

5.9 ± 10.1

5.2 ± 5.7

6.2 ± 11.4

0.493

CA199 (U/ml)

24.8 ± 54.6

18.7 ± 26.2

27.2 ± 62.2

0.305

Tumor site, n (%)

   

0.350

Colon

122 (56.7%)

31 (51.7%)

91 (58.7%)

 

Rectum

93 (43.3%)

29 (48.3%)

64 (41.3%)

 

Comorbidities, yes, n (%)

69 (32.1%)

17 (28.3%)

52 (33.5%)

0.463

Postoperative complications, yes, n (%)

34 (15.8%)

9 (15.0%)

25 (16.1%)

0.839

Surgical method

   

0.874

Open

49 (22.8%)

16 (26.7%)

43 (27.7%)

 

Laparoscopy

156 (77.2%)

44 (73.3%)

112 (72.3%)

 

Tumor size (cm)

4.1 (1.8 ± 0.1)

4.3 (2.0 ± 0.3)

4.086 (1.8 ± 0.1)

0.617

Depth of invasion

   

0.835

T1–2

45 (20.9%)

12 (20%)

33 (21.3%)

 

T3–4

170 (79.1%)

48 (80%)

122 (78.7%)

 

CRC stage, n (%)

   

0.907

I

36 (16.7%)

9 (15.0%)

27 (17.4%)

 

II

89 (41.4%)

25 (41.7%)

64 (41.3%)

 

III

90 (41.9%)

26 (43.3%)

64 (41.3%)

 
  1. Group differences were compared using the χ2 test or ANOVA.
  2. mCXI modified cachexia index, mCXI modified cachexia index, BMI body mass index, SMI Skeletal muscle mass index, WBC white blood cell, CRP C-reactive protein, CEA carcinoembryonic antigen, CA199 Carbohydrate antigen199, NLR neutrophil-to-lymphocyte ratio, CXI cachexia index.