Fig. 1: Advantages of iPSCs as compared to traditional modelling systems in modelling complex diseases.
From: Bridging population and cell: modelling complex diseases with human induced pluripotent stem cells
Traditional modelling systems are restricted to peripheral or post-mortem tissues, which have limited translational relevance for complex diseases (upper panel). iPSCs enable access to otherwise inaccessible cell types and multicellular systems derived from easily obtainable tissues (lower panel) and can therefore yield many more specific insights into complex disease mechanisms. iPSC induced pluripotent stem cell. Created with BioRender.
