Choroidal structures are visualized thoroughly by enhanced depth imaging optical coherence tomography (EDI-OCT) and choroidal OCT angiography (OCTA) with ultra-high resolution as a result of developments in the depth-resolved imaging approach. Recently, “choroidal caverns” lesions, associated with age-related macular degeneration (AMD) and pachychoroid diseases, were demonstrated by EDI-OCT and swept-source OCTA, in accord with histopathological results [1,2,3].

However, we consider that the term “choroidal caverns” lesions as an entity of the choroidal spectrum lesions, including intrachoroidal cavitation, choroidal cleft, and choroidal lipid globule caverns. In particular, some of the lesions have inherent correlations. The present review investigates the multimodal imaging characteristics of choroidal caverns lesions for similarities and differences to find inherent relationships among these lesions. This study was reviewed and approved by the Institutional Review Board of the First Hospital of China Medical University, and written informed consent was obtained from all patients for publication.

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