We read with interest Mandal et al’s recent publication demonstrating the role of topical antihypertensives in the failure of dacryocystorhinostomy (DCR) surgery by inducing inflammation, fibrosis and cicatrization at the site of anastomosis [1].

Factors responsible for successful outcomes of DCR surgery are precise localization of lacrimal sac, adequately sized osteotomy sufficient to expose the complete extent of lacrimal sac including fundus, marsupialization of the entire length of sac and mucosa to mucosa anastomosis to ensure healing by primary intention. The reported causes of failure are cicatricial ostium closure, scarred common canaliculus, obstructed distal canaliculi, organizing granuloma and bone neogenesis [2].

Log in or create a free account to read this content

Gain free access to this article, as well as selected content from this journal and more on nature.com

Access through your institution

or

Sign in or create an account
Continue with Google
Continue with ORCiD