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Rice JC, Liebenberg L, Scholtz RP, Torr G. Fatal air embolism during endoresection of choroidal melanoma. Retin Cases Brief Rep.2014;8:127–9. https://doi.org/10.1097/ICB.0000000000000021.
Joussen AM, Wong D. Egress of large quantities of heavy liquids from exposed choroid: a route for possible tumor dissemination via vortex veins in endoresection of choroidal melanoma. Graefes Arch Clin Exp Ophthalmol. 2015;253:177–8. https://doi.org/10.1007/s00417-014-2911-0.
Rojanaporn D, Tipsuriyaporn B, Chulalaksiriboon P, Virankabutra T, Morakul S, Damato B. Fatal Air Embolism after Choroidal Melanoma Endoresection without Air Infusion: A Case Report. Ocul Oncol Pathol. 2021;7:321–5. https://doi.org/10.1159/000518976.
Sass DJ, Van Dyke RA, Wood EH, Johnson SA, Didisheim P. Gas embolism due to intravenous FC 80 liquid fluorocarbon. J Appl Physiol. 1976;40:745–51. https://doi.org/10.1152/jappl.1976.40.5.745.
Lanaro R, De Capitani EM, Costa JL, Bucaretchi F, Togni L, Linden R, et al. Sudden deaths due to accidental intravenous injection of perfluorocarbon during MRI cranial examinations. Forensic Toxicol. 2014;32:323–30. https://doi.org/10.1007/s11419-014-0231-z.
Gasparović V, Ostojić R. Unexpected hemodialysis-related deaths in Croatia. J Nephrol. 2002;15:194–7.
Dias AMA, Caço AI, Coutinho JAP, Santos LMNBF, Piñeiro MM, Vega LF, et al. Thermodynamic properties of perfluoro-n-octane. Fluid Phase Equilib. 2004;225:39–47.
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HR, MRR, GKL, BED, LDC: conception, research, drafting, integrity check, final approval. MF, LW: drafting, revision, integrity check.
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Ruschen, H., Romano, M.R., Ferrara, M. et al. Perfluorocarbon syndrome—a possible, overlooked source of fatal gas embolism following uveal-melanoma endoresection. Eye 36, 2348–2349 (2022). https://doi.org/10.1038/s41433-022-02021-6
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DOI: https://doi.org/10.1038/s41433-022-02021-6
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