We read the article correlating the structural changes in the retina with the severity of thyroid eye disease (TED) with great interest. The authors highlighted the importance of close monitoring of the ganglion cell layer/inner plexiform layer (GCL/IPL) in moderate to severe TED to detect subclinical atrophy of the optic nerve [1].

The authors divided the cases into mild, moderate-to-severe, and Dysthyroid optic neuropathy (DON) categories [2]. The amount of proptosis, however, appears to overlap between the groups, and for a clearer depiction, data should have been presented in terms of confidence intervals. The exophthalmometry readings vary in different races, and the addition of control group readings would be desirable.

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